PIEZO2 antibody (AA 2575-2604)

Catalog No. ABIN7872967

The Rabbit Polyclonal anti-PIEZO2 antibody (ABIN7872967) specifically detects PIEZO2 in WB. The antibody is reactive with Human samples.

Quick Overview for PIEZO2 antibody (AA 2575-2604) (ABIN7872967)

Target: PIEZO2 (FAM38B) (Family with Sequence Similarity 38, Member B (FAM38B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIEZO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIEZO2 Antibody

Binding Specificity: AA 2575-2604

Purpose: PIEZO2 Antibody / FAM38B

Purification: Antigen affinity

Immunogen: A portion of amino acids 2575-2604 from the human protein was used as the immunogen for the PIEZO2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the PIEZO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PIEZO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PIEZO2

Target: PIEZO2 (FAM38B) (Family with Sequence Similarity 38, Member B (FAM38B))

Alternative Name: PIEZO2

Background: PIEZO2 (Piezo-type mechanosensitive ion channel component 2), also called Protein FAM38B, is a transmembrane protein that spans the cell membrane and acts as a sensor for mechanical stimuli. When external forces, such as touch or pressure, are applied to the cell membrane, PIEZO2 responds by opening up and allowing ions to flow into the cell. This influx of ions triggers a signal that is transmitted to the brain, allowing us to perceive and respond to the touch sensation. It also plays a critical role in a variety of other sensory functions, including proprioception (the ability to sense the position of our body in space) and hearing. Recent studies have uncovered even more functions of PIEZO2 beyond sensory perception. It has been found to be involved in regulating lung development, bone formation, and even cell migration.

UniProt: Q9H5I5