BUB1B antibody (AA 26-448)

Catalog No. ABIN7873003

The Mouse Monoclonal anti-BUB1B antibody (Clone 8B3) (ABIN7873003) specifically detects BUB1B in WB, FACS and IHC (p). The antibody is reactive with Human and Rat samples.

Quick Overview for BUB1B antibody (AA 26-448) (ABIN7873003)

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This BUB1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8B3

Product Details anti-BUB1B Antibody

Binding Specificity: AA 26-448

Purpose: BubR1 Antibody / BUB1B

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids K26-E448) was used as the immunogen for the BubR1 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the BubR1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the BubR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for BUB1B

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Alternative Name: BubR1

Background: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

UniProt: O60566