PYROXD1 antibody (AA 26-453)

Catalog No. ABIN7873006

The Rabbit Polyclonal anti-PYROXD1 antibody (ABIN7873006) specifically detects PYROXD1 in WB, FACS, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PYROXD1 antibody (AA 26-453) (ABIN7873006)

Target: PYROXD1 (Pyridine Nucleotide-Disulphide Oxidoreductase Domain 1 (PYROXD1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYROXD1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)

Product Details anti-PYROXD1 Antibody

Binding Specificity: AA 26-453

Purpose: PYROXD1 Antibody / Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A26-N453) was used as the immunogen for the PYROXD1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PYROXD1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PYROXD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PYROXD1

Target: PYROXD1 (Pyridine Nucleotide-Disulphide Oxidoreductase Domain 1 (PYROXD1))

Alternative Name: PYROXD1

Background: Pyridine nucleotide-disulphide oxidoreductase domain 1 is a protein that in humans is encoded by the PYROXD1 gene. It is mapped to 12p12.1. This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other proteins. The encoded protein belongs to the class I pyridine nucleotide-disulphide oxidoreductase family but lacks the C-terminal dimerization domain found in other family members and instead has a C-terminal nitrile reductase domain. It localizes to the nucleus and to striated sarcomeric compartments. Naturally occurring mutations in this gene cause early-onset myopathy with internalized nuclei and myofibrillar disorganization. A pseudogene of this gene has been defined on chromosome 11.

UniProt: Q8WU10