Azurocidin antibody (AA 27-245)

Catalog No. ABIN7873103

This Rabbit Polyclonal antibody specifically detects Azurocidin in WB, ELISA, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Azurocidin antibody (AA 27-245) (ABIN7873103)

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Azurocidin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Azurocidin Antibody

Binding Specificity: AA 27-245

Purpose: Azurocidin Antibody / AZU1 / CAP37

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids I27-N245) was used as the immunogen for the Azurocidin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Azurocidin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Azurocidin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Alternative Name: Azurocidin

Background: Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

UniProt: P20160