CASK antibody (AA 27-492)

Catalog No. ABIN7873123

The Rabbit Polyclonal anti-CASK antibody (ABIN7873123) specifically detects CASK in IF and IHC (p). The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for CASK antibody (AA 27-492) (ABIN7873123)

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASK antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CASK Antibody

Binding Specificity: AA 27-492

Purpose: Zebrafish Cask Antibody / Caska

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Cask recombinant protein (amino acids R27-D492) was used as the immunogen for the Zebrafish Cask antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Cask antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Cask antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CASK

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Alternative Name: Cask

Background: Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q910A4

Pathways: Synaptic Vesicle Exocytosis