ZFP36L1 antibody (AA 28-502)

Catalog No. ABIN7873270

The Rabbit Polyclonal anti-ZFP36L1 antibody (ABIN7873270) specifically detects ZFP36L1 in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for ZFP36L1 antibody (AA 28-502) (ABIN7873270)

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-ZFP36L1 Antibody

Binding Specificity: AA 28-502

Purpose: CMG-1 Antibody / Capillary morphogenesis gene 1 / IFT74

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids I28-H502) was used as the immunogen for the CMG-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CMG-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CMG-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Alternative Name: CMG-1

Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

UniProt: Q96LB3