NPY antibody (AA 28-62)

Catalog No. ABIN7873279

The Rabbit Polyclonal anti-NPY antibody (ABIN7873279) specifically detects NPY in IHC (p). The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for NPY antibody (AA 28-62) (ABIN7873279)

Target: NPY (Neuropeptide Y (NPY))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NPY Antibody

Binding Specificity: AA 28-62

Purpose: Zebrafish Neuropeptide Y Antibody / Npy

Purification: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Neuropeptide Y recombinant protein (amino acids G28-Q62) was used as the immunogen for the Zebrafish Neuropeptide Y antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Neuropeptide Y antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Neuropeptide Y antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NPY

Target: NPY (Neuropeptide Y (NPY))

Alternative Name: Neuropeptide Y

Background: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

UniProt: Q9I8P3

Pathways: Feeding Behaviour