RORC antibody (AA 286-511)

Catalog No. ABIN7873318

The Rabbit Polyclonal anti-RORC antibody (ABIN7873318) specifically detects RORC in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for RORC antibody (AA 286-511) (ABIN7873318)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RORC Antibody

Binding Specificity: AA 286-511

Purpose: ROR gamma Antibody / RORC

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q286-E511) was used as the immunogen for the ROR gamma antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ROR gamma antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ROR gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: ROR gamma

Background: RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway