CCDC109B antibody (AA 291-320)
Quick Overview for CCDC109B antibody (AA 291-320) (ABIN7873446)
Target
See all CCDC109B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 291-320
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Purpose
- MCUB Antibody / CCDC109B / C109B
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 291-320 from the human protein was used as the immunogen for the MCUB antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the MCUB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the MCUB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))
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Alternative Name
- MCUB
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Background
- MCUB, or Calcium uniporter regulatory subunit MCUb, mitochondrial, is involved in various cellular processes, including metabolism, cell signaling, and cell death. By controlling the influx of calcium into mitochondria, MCUB helps to regulate mitochondrial function and protect cells from damage. Research has shown that dysregulation of MCUB can lead to mitochondrial dysfunction and contribute to the development of various diseases, including neurodegenerative disorders and cancer.
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UniProt
- Q9NWR8
Target
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