DBF4 antibody (AA 295-665)

Catalog No. ABIN7873463

This Rabbit Polyclonal antibody specifically detects DBF4 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for DBF4 antibody (AA 295-665) (ABIN7873463)

Target: DBF4 (DBF4 Homolog (DBF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-DBF4 Antibody

Binding Specificity: AA 295-665

Purpose: DBF4 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Y295-S665) was used as the immunogen for the DBF4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DBF4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DBF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DBF4

Target: DBF4 (DBF4 Homolog (DBF4))

Alternative Name: DBF4

Background: Using both gain- and loss-of-function experiments, it was found that Xenopus Dbf4 inhibited canonical Wnt signaling. Depletion of endogenous Dbf4 did not disturb gastrulation movements or early organizer genes, but resulted in embryos with morphologically defective heart and eyes and suppressed cardiac markers. The function of Dbf4 in heart development appeared to be independent of its role in the cell cycle. Dbf4 interacted physically and functionally with Frodo, a context-dependent regulator of Wnt signaling.

UniProt: Q9UBU7

Pathways: Mitotic G1-G1/S Phases, DNA Replication