STS antibody (AA 297-547)

Catalog No. ABIN7873482

The Rabbit Polyclonal anti-STS antibody is suitable to detect STS in samples from Human. It has been validated for WB, ELISA, FACS and IHC (p).

Quick Overview for STS antibody (AA 297-547) (ABIN7873482)

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-STS Antibody

Binding Specificity: AA 297-547

Purpose: Steryl-sulfatase Antibody / Steroid sulfatase / Arylsulfatase C

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K297-Q547) was used as the immunogen for the Steryl-sulfatase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Steryl-sulfatase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Steryl-sulfatase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: Steryl-sulfatase

Background: Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis