SERBP1 antibody (AA 3-139)

Catalog No. ABIN7873492

The Mouse Monoclonal anti-SERBP1 antibody (Clone SERBP1-3494) (ABIN7873492) specifically detects SERBP1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SERBP1 antibody (AA 3-139) (ABIN7873492)

Target: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: SERBP1-3494

Product Details anti-SERBP1 Antibody

Binding Specificity: AA 3-139

Purpose: SERBP1 Antibody / PAI-RBP1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the SERBP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for SERBP1

Target: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Alternative Name: SERBP1

Background: SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.

UniProt: Q8NC51