AGL antibody (AA 3-265)

Catalog No. ABIN7873529

This Rabbit Polyclonal antibody specifically detects AGL in WB, IF, ELISA, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AGL antibody (AA 3-265) (ABIN7873529)

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AGL Antibody

Binding Specificity: AA 3-265

Purpose: 4-Alpha-glucanotransferase Antibody / AGL / Glycogen debranching enzyme

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids H3-K265) was used as the immunogen for the 4-Alpha-glucanotransferase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the 4-Alpha-glucanotransferase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the 4-Alpha-glucanotransferase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for AGL

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Alternative Name: 4-Alpha-glucanotransferase

Background: This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

UniProt: P35573

Pathways: Cellular Glucan Metabolic Process