LRG1 antibody (AA 30-180)

Catalog No. ABIN7873571

This Mouse Monoclonal antibody specifically detects LRG1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for LRG1 antibody (AA 30-180) (ABIN7873571)

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRG1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LRG1-4883

Product Details anti-LRG1 Antibody

Binding Specificity: AA 30-180

Purpose: Leucine-rich alpha-2-glycoprotein Antibody / LRG1

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 30-180 was used as the immunogen for the Leucine-rich alpha-2-glycoprotein antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Leucine-rich alpha-2-glycoprotein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Leucine-rich alpha-2-glycoprotein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Alternative Name: Leucine-rich alpha-2-glycoprotein

Background: LRG1 (leucine-rich 2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

UniProt: P02750

Pathways: Brown Fat Cell Differentiation