SSTR2 antibody (AA 300-500)

Catalog No. ABIN7873651

The Mouse Monoclonal anti-SSTR2 antibody (Clone SSTR2-7532) (ABIN7873651) specifically detects SSTR2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for SSTR2 antibody (AA 300-500) (ABIN7873651)

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SSTR2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SSTR2-7532

Product Details anti-SSTR2 Antibody

Binding Specificity: AA 300-500

Purpose: SSTR2 Antibody / Somatostatin Receptor 2

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 300-500) from the human protein was used as the immunogen for the SSTR2 antibody.

Isotype: IgG2b, lambda

Application Details

Application Notes: Optimal dilution of the SSTR2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SSTR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Alternative Name: SSTR2

Background: SSTRs (for somatostatin receptors) represent a family of G protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.

UniProt: P30874