PLA2R1 antibody (AA 300-600)

Catalog No. ABIN7873695

The Mouse Monoclonal anti-PLA2R1 antibody is suitable to detect PLA2R1 in samples from Human. It has been validated for IHC (p).

Quick Overview for PLA2R1 antibody (AA 300-600) (ABIN7873695)

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLA2R1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PLA2R1-4896

Product Details anti-PLA2R1 Antibody

Binding Specificity: AA 300-600

Purpose: Secretory phospholipase A2 receptor Antibody / PLA2R1

Purification: Protein G affinity

Immunogen: A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the Secretory phospholipase A2 receptor antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Secretory phospholipase A2 receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Secretory phospholipase A2 receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PLA2R1

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Alternative Name: Secretory phospholipase A2 receptor

Background: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus