PLA2R1 antibody (AA 300-600)

Catalog No. ABIN7873698

The Mouse Monoclonal anti-PLA2R1 antibody is suitable to detect PLA2R1 in samples from Human. It has been validated for IHC (p).

Quick Overview for PLA2R1 antibody (AA 300-600) (ABIN7873698)

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLA2R1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PLA2R1-4893

Product Details anti-PLA2R1 Antibody

Binding Specificity: AA 300-600

Purpose: PLA2R1 Antibody / Phospholipase A2 receptor 1 (azide and preservative free)

Purification: Protein A affinity

Immunogen: A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the PLA2R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PLA2R1

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Alternative Name: PLA2R1

Background: Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. [UniProt]

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus