CBS antibody (AA 301-330)

Catalog No. ABIN7873704

The Rabbit Polyclonal anti-CBS antibody is suitable to detect CBS in samples from Human, Mouse and Rat. It has been validated for WB, IF, IHC (p) and FACS.

Quick Overview for CBS antibody (AA 301-330) (ABIN7873704)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-CBS Antibody

Binding Specificity: AA 301-330

Purpose: CBS Antibody / Cystathionine Beta Synthase

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 301-330 from the human protein were used as the immunogen for the CBS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the CBS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CBS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background: CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

UniProt: P35520