FPGS antibody (AA 304-330)
Quick Overview for FPGS antibody (AA 304-330) (ABIN7873726)
Target
See all FPGS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 304-330
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Purpose
- FPGS Antibody / Folylpolyglutamate synthase
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 304-330 from the human protein was used as the immunogen for the FPGS antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the FPGS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the FPGS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FPGS (Folylpolyglutamate Synthase (FPGS))
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Alternative Name
- FPGS
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Background
- FPGS is the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives.
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UniProt
- Q05932
Target
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