LRRC47 antibody (AA 309-583)

Catalog No. ABIN7873742

This Rabbit Polyclonal antibody specifically detects LRRC47 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for LRRC47 antibody (AA 309-583) (ABIN7873742)

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC47 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-LRRC47 Antibody

Binding Specificity: AA 309-583

Purpose: LRRC47 Antibody / Leucine-rich repeat-containing protein 47

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids L309-R583) was used as the immunogen for the LRRC47 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LRRC47 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LRRC47 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LRRC47

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Alternative Name: LRRC47

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

UniProt: Q8N1G4