LRRC47 antibody (AA 309-583)

Catalog No. ABIN7601245

The Rabbit Polyclonal anti-LRRC47 antibody is suitable to detect LRRC47 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for LRRC47 antibody (AA 309-583) (ABIN7601245)

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC47 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-LRRC47 Antibody

Binding Specificity: AA 309-583

Purpose: Anti-LRRC47 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-LRRC47 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC47 recombinant protein (Position: L309-R583).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LRRC47

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Alternative Name: LRRC47

Background:

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene Full Name: leucine rich repeat containing 47

Molecular Weight: 68 kDa

Gene ID: 57470

UniProt: Q8N1G4