The Mouse Monoclonal anti-PODXL antibody (Clone rPODXL-2184) (ABIN7873807) specifically detects PODXL in ELISA.
The antibody is reactive with Human samples.
Optimal dilution of the recombinant Podocalyxin antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store the recombinant Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
PODXL
(Podocalyxin-Like (PODXL))
Alternative Name
Podocalyxin
Background
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.