Recombinant PODXL antibody (AA 310-447)
Quick Overview for Recombinant PODXL antibody (AA 310-447) (ABIN7873807)
Target
See all PODXL AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 310-447
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Purpose
- Recombinant Podocalyxin Antibody
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Purification
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 310-447 from the human protein was used as the immunogen for the recombinant Podocalyxin antibody.
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Isotype
- IgG1, kappa
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Application Notes
- Optimal dilution of the recombinant Podocalyxin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the recombinant Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- PODXL (Podocalyxin-Like (PODXL))
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Alternative Name
- Podocalyxin
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Background
- Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
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UniProt
- O00592
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Pathways
- Tube Formation
Target
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