PODXL antibody (AA 310-447)

Catalog No. ABIN7873811

This Mouse Monoclonal antibody specifically detects PODXL in IHC (p). It exhibits reactivity toward Human.

Quick Overview for PODXL antibody (AA 310-447) (ABIN7873811)

Target: PODXL (Podocalyxin-Like (PODXL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PODXL-2185

Product Details anti-PODXL Antibody

Binding Specificity: AA 310-447

Purpose: Podocalyxin Antibody

Purification: Protein G affinity

Immunogen: A portion of amino acids 310-447 from the human protein was used as the immunogen for the Podocalyxin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Podocalyxin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: Podocalyxin

Background: Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

UniProt: O00592

Pathways: Tube Formation