TNIP1
Reactivity: Human, Horse, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the ABIN-1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the ABIN-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
TNIP1
(TNFAIP3 Interacting Protein 1 (TNIP1))
Alternative Name
ABIN-1
Background
TNFAIP3-interacting protein 1, also called ABIN-1 or A20-binding inhibitor of NF-kappa-B activation 1, is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.