ALDH1A1 antibody (AA 315-434)

Catalog No. ABIN7873873

The Mouse Monoclonal anti-ALDH1A1 antibody (Clone ALDH1A1-1381) (ABIN7873873) specifically detects ALDH1A1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ALDH1A1 antibody (AA 315-434) (ABIN7873873)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ALDH1A1-1381

Product Details anti-ALDH1A1 Antibody

Binding Specificity: AA 315-434

Purpose: ALDH1A1 Antibody / Acetaldehyde dehydrogenase 1

Purification: Protein G affinity chromatography

Immunogen: A human recombinant partial ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the ALDH1A1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the ALDH1A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: ALDH1A1

Background: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

UniProt: P00352

Pathways: Dopaminergic Neurogenesis