DDC antibody (AA 32-61)

Catalog No. ABIN7873933

The Rabbit Polyclonal anti-DDC antibody (ABIN7873933) specifically detects DDC in WB, FACS, IF and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for DDC antibody (AA 32-61) (ABIN7873933)

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDC antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DDC Antibody

Binding Specificity: AA 32-61

Purpose: AADC Antibody / DOPA Decarboxylase / DDC

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 32-61 from the human protein was used as the immunogen for the AADC antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the AADCantibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the AADC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Alternative Name: AADC

Background: This protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency.

UniProt: P20711

Pathways: Dopaminergic Neurogenesis