CTBP2 antibody (C-Term)

Catalog No. ABIN7873943

This Mouse Monoclonal antibody specifically detects CTBP2 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CTBP2 antibody (C-Term) (ABIN7873943)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CTBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7F3E1

Product Details anti-CTBP2 Antibody

Binding Specificity: AA 321-445, C-Term

Purpose: C-terminal-binding protein 2 Antibody / CTBP2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids H321-Q445) was used as the immunogen for the C-terminal-binding protein 2 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the C-terminal-binding protein 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the C-terminal-binding protein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Alternative Name: C-terminal-binding protein 2

Background: The E1a region of group C adenoviruses encodes 2 nearly identical proteins that are largely responsible for the oncogenic properties of adenoviruses. The CTBP1 protein binds to the C-terminal half of these E1A proteins. It's predicted that CTBP2 is a 445-amino acid protein and it is 72 % identical to CTBP1. The CTBP2 gene is mapped to chromosome 10q26.13. CTBP2 is a mammalian corepressor that targets diverse transcriptional regulators. It bounds the short medial portion of delta-EF1 containing the PLDLSL motif and it enhances transrepression activity of delta-EF1.

UniProt: P56545