CLPX antibody (AA 327-564)

Catalog No. ABIN7873979

This Rabbit Polyclonal antibody specifically detects CLPX in WB. It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for CLPX antibody (AA 327-564) (ABIN7873979)

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLPX Antibody

Binding Specificity: AA 327-564

Purpose: Zebrafish Clpx Antibody / Isoforms a & b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Clpxa/b recombinant protein (amino acids A327-L564) was used as the immunogen for the Zebrafish Clpx antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Clpx antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Clpx antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CLPX

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Alternative Name: Clpx

Background: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial is an enzyme that in humans is encoded by the CLPX gene. This protein is a member of the family of AAA Proteins (AAA+ ATPase) and is to form the protein complex of Clp protease. The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.