Glucuronidase beta antibody (AA 335-362)

Catalog No. ABIN7874037

The Rabbit Polyclonal anti-Glucuronidase beta antibody is suitable to detect Glucuronidase beta in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for Glucuronidase beta antibody (AA 335-362) (ABIN7874037)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 335-362

Purpose: Beta Glucuronidase Antibody / Gusb

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 335-362 from the human protein was used as the immunogen for the Beta Glucuronidase antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Beta Glucuronidase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Beta Glucuronidase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: Beta Glucuronidase

Background: The GUSB gene encodes beta-glucuronidase, a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987). The GUSB gene is mutated in mucopolysaccharidosis type VII.

UniProt: P08236

Pathways: Glycosaminoglycan Metabolic Process