TK2 antibody (AA 34-265)

Catalog No. ABIN7874071

The Rabbit Polyclonal anti-TK2 antibody (ABIN7874071) specifically detects TK2 in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for TK2 antibody (AA 34-265) (ABIN7874071)

Target: TK2 (Thymidine Kinase 2, Mitochondrial (TK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TK2 Antibody

Binding Specificity: AA 34-265

Purpose: Thymidine Kinase 2 Antibody / TK2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids V34-P265) was used as the immunogen for the Thymidine Kinase 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Thymidine Kinase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Thymidine Kinase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TK2

Target: TK2 (Thymidine Kinase 2, Mitochondrial (TK2))

Alternative Name: Thymidine Kinase 2

Background: Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria.

UniProt: O00142

Pathways: Mitotic G1-G1/S Phases