CD86 antibody (AA 35-221)

Catalog No. ABIN7874157

The Rabbit Polyclonal anti-CD86 antibody is suitable to detect CD86 in samples from Mouse and Rat. It has been validated for FACS, WB, ELISA and IHC (p).

Quick Overview for CD86 antibody (AA 35-221) (ABIN7874157)

Target: CD86

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD86 Antibody

Binding Specificity: AA 35-221

Purpose: Cd86 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids T35-E221) was used as the immunogen for the Cd86 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cd86 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cd86 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CD86

Target: CD86

Alternative Name: Cd86

Background: Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. Using fluorescence in situ hybridization mapping, the CD86, like CD80, was mapped to human 3q21. The antigen presentation coactivators B71 and B72, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma.

UniProt: P42082

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation