LGI1 antibody (AA 35-557)

Catalog No. ABIN7874172

The Rabbit Polyclonal anti-LGI1 antibody is suitable to detect LGI1 in samples from Mouse, Human and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for LGI1 antibody (AA 35-557) (ABIN7874172)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-LGI1 Antibody

Binding Specificity: AA 35-557

Purpose: LGI1 Antibody / Leucine-rich glioma inactivated 1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids K35-A557) was used as the immunogen for the LGI1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LGI1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LGI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Alternative Name: LGI1

Background: Leucine-rich, glioma inactivated 1, also known as LGI1, is a protein which in humans is encoded by the LGI1 gene. This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

UniProt: O95970