Scinderin antibody (AA 35-617)

Catalog No. ABIN7874176

The Rabbit Polyclonal anti-Scinderin antibody (ABIN7874176) specifically detects Scinderin in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Scinderin antibody (AA 35-617) (ABIN7874176)

Target: Scinderin (SCIN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Scinderin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Scinderin Antibody

Binding Specificity: AA 35-617

Purpose: Scinderin Antibody / SCIN

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids S35-Y617) was used as the immunogen for the Scinderin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Scinderin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Scinderin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Scinderin

Target: Scinderin (SCIN)

Alternative Name: Scinderin

Background: Scinderin (also known as Adseverin) is a protein that in humans is encoded by the SCIN gene. Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).

UniProt: Q9Y6U3

Pathways: Regulation of Actin Filament Polymerization