Recombinant FOXP1 antibody (AA 350-450)

Catalog No. ABIN7874193

The Rabbit Monoclonal anti-FOXP1 antibody is suitable to detect FOXP1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant FOXP1 antibody (AA 350-450) (ABIN7874193)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXP1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: FOXP1-9381R

Product Details anti-FOXP1 Antibody

Binding Specificity: AA 350-450

Purpose: FOXP1 Antibody / Forkhead box protein P1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 350-450) of human FOXP1 protein was used as the immunogen for the FOXP1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the FOXP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the FOXP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Alternative Name: FOXP1

Background: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (~80 % +) for FOXP1 is needed to achieve high specificity for the ABC subtype.

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response