Recombinant Cadherin-16 antibody (AA 350-550)

Catalog No. ABIN7874221

The Rabbit Monoclonal anti-Cadherin-16 antibody (Clone CDH16-8800R) (ABIN7874221) specifically detects Cadherin-16 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Cadherin-16 antibody (AA 350-550) (ABIN7874221)

Target: Cadherin-16 (CDH16)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CDH16-8800R

Product Details anti-Cadherin-16 Antibody

Binding Specificity: AA 350-550

Purpose: Ksp-Cadherin Antibody / CDH16 (azide and preservative free)

Purification: Protein A affinity

Immunogen: A recombinant partial protein sequence (within amino acids 350-550) from the human protein was used as the immunogen for the Ksp-Cadherin antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Ksp-Cadherin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Ksp-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: Ksp-Cadherin

Background: This mAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309