GFRAL antibody (AA 366-394)

Catalog No. ABIN7874347

The Rabbit Polyclonal anti-GFRAL antibody (ABIN7874347) specifically detects GFRAL in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for GFRAL antibody (AA 366-394) (ABIN7874347)

Target: GFRAL (GDNF Family Receptor alpha Like (GFRAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRAL antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GFRAL Antibody

Binding Specificity: AA 366-394

Purpose: GFRAL Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 366-394 from the human protein was used as the immunogen for the GFRAL antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the GFRAL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the GFRAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GFRAL

Target: GFRAL (GDNF Family Receptor alpha Like (GFRAL))

Alternative Name: GFRAL

Background: Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt]

UniProt: Q6UXV0