ZNF202 antibody (AA 37-132)
Quick Overview for ZNF202 antibody (AA 37-132) (ABIN7874390)
Target
See all ZNF202 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Binding Specificity
- AA 37-132
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Purpose
- ZNF202 Antibody (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- A recombinant partial protein (within amino acids 37-132) from the human protein was used as the immunogen for the ZNF202 antibody.
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Isotype
- IgG2a
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Application Notes
- Optimal dilution of the ZNF202 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the ZNF202 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ZNF202 (Zinc Finger Protein 202 (ZNF202))
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Alternative Name
- ZNF202
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Background
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202), also known as ZKSCAN10, is a 648 amino acid protein that contains eight C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis, ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins, including lipoprotein particles, transporters involved in lipid homeostasis, enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung, ovarian and breast cancer. Two isoforms of ZNF202, designated a and b, exist due to alternative splicing events
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UniProt
- O95125
Target
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