CENPH antibody (AA 37-247)
Quick Overview for CENPH antibody (AA 37-247) (ABIN7874392)
Target
See all CENPH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 37-247
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Purpose
- CENPH Antibody
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Purification
- Antigen affinity purified
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Immunogen
- Recombinant human protein (amino acids E37-M247) was used as the immunogen for the CENPH antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the CENPH antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the CENPH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CENPH (Centromere Protein H (CENPH))
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Alternative Name
- CENPH
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Background
- Centromere protein H is a protein that in humans is encoded by the CENPH gene. Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
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UniProt
- Q9H3R5
Target
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