ATIC antibody (AA 37-592)

Catalog No. ABIN7874410

The Rabbit Polyclonal anti-ATIC antibody (ABIN7874410) specifically detects ATIC in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ATIC antibody (AA 37-592) (ABIN7874410)

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATIC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ATIC Antibody

Binding Specificity: AA 37-592

Purpose: ATIC Antibody / AICAR transformylase / PURH

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids T37-H592) was used as the immunogen for the ATIC antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATIC antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATIC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATIC

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: ATIC

Background: Bifunctional purine biosynthesis protein PURH is a protein that in humans is encoded by the ATIC gene. This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

UniProt: P31939