Cadherin-16 antibody (AA 371-507)

Catalog No. ABIN7874426

This Mouse Monoclonal antibody specifically detects Cadherin-16 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Cadherin-16 antibody (AA 371-507) (ABIN7874426)

Target: Cadherin-16 (CDH16)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cadherin-16 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH16-2448

Product Details anti-Cadherin-16 Antibody

Binding Specificity: AA 371-507

Purpose: CDH16 Antibody / Cadherin 16

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 371-507) was used as the immunogen for the CDH16 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CDH16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CDH16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cadherin-16

Target: Cadherin-16 (CDH16)

Alternative Name: CDH16

Background: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin (also called CDH16 and Cadherin 16). Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309