OB Cadherin antibody (AA 371-796)

Catalog No. ABIN7874428

The Rabbit Polyclonal anti-OB Cadherin antibody (ABIN7874428) specifically detects OB Cadherin in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for OB Cadherin antibody (AA 371-796) (ABIN7874428)

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OB Cadherin Antibody

Binding Specificity: AA 371-796

Purpose: Cadherin 11 Antibody / CDH11 / OB-Cadherin

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids K371-S796) was used as the immunogen for the Cadherin 11 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cadherin 11 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cadherin 11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: Cadherin 11

Background: Cadherin-11, also called Osteoblast cadherin or OB Cadherin, is a protein that in humans is encoded by the CDH11 gene. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

UniProt: P55287