SHROOM1 antibody (AA 371-807)

Catalog No. ABIN7874429

This Rabbit Polyclonal antibody specifically detects SHROOM1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SHROOM1 antibody (AA 371-807) (ABIN7874429)

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SHROOM1 Antibody

Binding Specificity: AA 371-807

Purpose: SHROOM1 Antibody / APXL2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R371-D807) was used as the immunogen for the SHROOM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SHROOM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SHROOM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SHROOM1

Target: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Alternative Name: SHROOM1

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

UniProt: Q2M3G4