FTL antibody (AA 38-165) (Biotin)

Catalog No. ABIN7874494

The Biotin-conjugated Mouse Monoclonal anti-FTL antibody (Clone FTL-1386) (ABIN7874494) specifically detects FTL in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FTL antibody (AA 38-165) (Biotin) (ABIN7874494)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-1386

Product Details anti-FTL Antibody (Biotin)

Binding Specificity: AA 38-165

Purpose: FTL Antibody / Biotin Conjugate

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the FTL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the FTL antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: FTL

Background: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis