FTL antibody (Light Chain)

Catalog No. ABIN7874495

This Mouse Monoclonal antibody specifically detects FTL in IHC (p). It exhibits reactivity toward Human.

Quick Overview for FTL antibody (Light Chain) (ABIN7874495)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: FTL-3100

Product Details anti-FTL Antibody

Binding Specificity: AA 38-165, Light Chain

Purpose: FTL Antibody / Ferritin Light Chain (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the FTL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: FTL

Background: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyper-ferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis