SGCE antibody (AA 38-407)

Catalog No. ABIN7874505

The Rabbit Polyclonal anti-SGCE antibody is suitable to detect SGCE in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and FACS.

Quick Overview for SGCE antibody (AA 38-407) (ABIN7874505)

Target: SGCE (Sarcoglycan, epsilon (SGCE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SGCE Antibody

Binding Specificity: AA 38-407

Purpose: SGCE Antibody / Epsilon-sarcoglycan

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Y38-D407) was used as the immunogen for the SGCE antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SGCE antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SGCE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SGCE

Target: SGCE (Sarcoglycan, epsilon (SGCE))

Alternative Name: SGCE

Background: Epsilon-sarcoglycan is a protein that in humans is encoded by the SGCE gene. This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2.

UniProt: O43556