ASCL2 antibody (AA 38-65)

Catalog No. ABIN7874514

The Rabbit Polyclonal anti-ASCL2 antibody is suitable to detect ASCL2 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for ASCL2 antibody (AA 38-65) (ABIN7874514)

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASCL2 Antibody

Binding Specificity: AA 38-65

Purpose: ASCL2 Antibody / Achaete-scute homolog 2

Purification: Antigen affinity

Immunogen: A portion of amino acids 38-65 from the human protein was used as the immunogen for this ASCL2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ASCL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the ASCL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ASCL2

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Alternative Name: ASCL2

Background: ASCL2 belongs to a family of genes that are involved in determining cell fate and differentiation, particularly in the development of tissues such as the nervous system and the intestines. Studies have shown that ASCL2 plays a critical role in regulating the self-renewal and differentiation of stem cells, making it a key player in tissue regeneration and repair processes. One of the most fascinating aspects of ASCL2 is its ability to control the expression of other genes, essentially acting as a master regulator in the cellular development process. By activating or repressing specific genes, ASCL2 can influence the fate of a cell and dictate its ultimate function within a tissue or organ. ASCL2 has been implicated in a variety of diseases and conditions, including certain types of cancers where its dysregulation can lead to uncontrolled cell growth and proliferation.

UniProt: Q96QA5

Pathways: Stem Cell Maintenance