MMP10 antibody (AA 380-410)

Catalog No. ABIN7874520

The Mouse Polyclonal anti-MMP10 antibody is suitable to detect MMP10 in samples from Human. It has been validated for WB, IF and IHC (p).

Quick Overview for MMP10 antibody (AA 380-410) (ABIN7874520)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMP10 Antibody

Binding Specificity: AA 380-410

Purpose: MMP10 Antibody| Matrix metalloproteinase 10

Immunogen: A portion of amino acids 380-410 from the human protein was used as the immunogen for the MMP10 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MMP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the MMP10 antibody at -20oC.

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP10

Background: MMP10 belongs to the matrix metalloproteinase family, a group of enzymes that play a key role in tissue remodeling by degrading various components of the extracellular matrix. Specifically, MMP10 is known for its ability to degrade collagen, a major structural component of connective tissue. By breaking down collagen, MMP10 helps to facilitate the turnover of damaged tissues and promote the regeneration of new, healthy tissue. One of the most intriguing aspects of MMP10 is its regulation in response to different stimuli. For example, MMP10 expression can be induced by factors such as growth factors, cytokines, and mechanical stress. This dynamic regulation allows MMP10 to respond to changing environmental conditions and play a crucial role in processes such as tissue repair and inflammation. Research has also shown that dysregulation of MMP10 activity can have detrimental effects on tissue homeostasis. For example, overexpression of MMP10 has been linked to various pathological conditions, including cancer metastasis and inflammatory diseases. On the other hand, decreased MMP10 activity has been associated with impaired wound healing and fibrosis.

UniProt: P09238