Myosin VI antibody (AA 383-786)

Catalog No. ABIN7874533

The Rabbit Polyclonal anti-Myosin VI antibody (ABIN7874533) specifically detects Myosin VI in WB, ELISA and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for Myosin VI antibody (AA 383-786) (ABIN7874533)

Target: Myosin VI (MYO6)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Myosin VI Antibody

Binding Specificity: AA 383-786

Purpose: MYO6 Antibody / Unconventional Myosin-6

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (Q383-H786) was used as the immunogen for the MYO6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MYO6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MYO6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: MYO6

Background: Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization