SP1 antibody (AA 384-603)

Catalog No. ABIN7874536

The Mouse Monoclonal anti-SP1 antibody (Clone 3C4C3) (ABIN7874536) specifically detects SP1 in WB, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for SP1 antibody (AA 384-603) (ABIN7874536)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 3C4C3

Product Details anti-SP1 Antibody

Binding Specificity: AA 384-603

Purpose: Transcription factor SP1 Antibody / Specificity protein 1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q384-A603) was used as the immunogen for the Transcription factor SP1 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Transcription factor SP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Transcription factor SP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Alternative Name: Transcription factor SP1

Background: Transcription factor Sp1, also known as Specificity protein 1 is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction