RNASEH2B antibody (AA 39-260)

Catalog No. ABIN7874594

This Rabbit Polyclonal antibody specifically detects RNASEH2B in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for RNASEH2B antibody (AA 39-260) (ABIN7874594)

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEH2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-RNASEH2B Antibody

Binding Specificity: AA 39-260

Purpose: RNase H2 subunit B Antibody / RNASEH2B

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K39-E260) was used as the immunogen for the RNase H2 subunit B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RNase H2 subunit B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RNase H2 subunit B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RNASEH2B

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Alternative Name: RNase H2 subunit B

Background: Ribonuclease H2, subunit B is a protein that in humans is encoded by the RNASEH2B gene. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

UniProt: Q5TBB1